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Found 10 Enz. Inhib. hit(s) with Target = 'Glutamate receptor 1' and Ligand = 'BDBM50002369'
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataKi:  477nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataKi:  7.45E+3nMAssay Description:Compound was tested for binding affinity against human Ionotropic glutamate receptor AMPA 1 in HEK293 cells using [3H]-AMPA as radioligandMore data for this Ligand-Target Pair
TargetGlutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataKi:  7.45E+3nMAssay Description:Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataKi:  7.50E+3nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 1 using cell membranes prepared from HEK293 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataEC50:  6.00E+4nMAssay Description:Agonist activity at recombinant GluA1 receptor flop isoform expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataEC50:  2.30E+4nMAssay Description:Agonist activity at rat recombinant GluR1 flip isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM ass...Checked by AuthorMore data for this Ligand-Target Pair
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataEC50:  2.30E+4nMAssay Description:Agonist activity at rat recombinant GluA1 receptor flip isoform expressed in HEK293 cells assessed as effect on cyclothiazide-induced calcium flux by...More data for this Ligand-Target Pair
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataEC50:  2.70E+4nMAssay Description:Agonist activity at rat recombinant GluA1 receptor flop isoform expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetGlutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataEC50:  7.51E+3nMAssay Description:Agonist activity at recombinant GluA1 receptor flip isoform expressed in Xenopus oocytes co-expressing gamma2-TARPMore data for this Ligand-Target Pair
TargetGlutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataEC50:  7.30E+4nMAssay Description:Agonist activity at recombinant GluA1 receptor flip isoform expressed in Xenopus oocytesMore data for this Ligand-Target Pair