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Found 3 Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM198751'
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198751(BDBM198752 | BDBM198827 | US9221796, 53, P-1)
Affinity DataKi:  5.80nM ΔG°:  -51.0kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198751(BDBM198752 | BDBM198827 | US9221796, 53, P-1)
Affinity DataKi:  36nM ΔG°:  -46.0kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198751(BDBM198752 | BDBM198827 | US9221796, 53, P-1)
Affinity DataKi:  1.10E+3nM ΔG°:  -36.9kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent