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Found 2 Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM310966'
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM310966(US10155727, Example 20 | USRE49517, Example 20)
Affinity DataIC50:  22.2nMAssay Description:After thawing on the day of the assay, a 5 ml membrane aliquot was centrifuged at 48000 g for 30 min at 4° C. The pellet was resuspended in 5 ml of 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM310966(US10155727, Example 20 | USRE49517, Example 20)
Affinity DataIC50:  5.97E+3nMAssay Description:The medium was removed and the cells were loaded with 200 μl loading buffer (Molecular Devices) in Mg2+-free HBPS containing 100 μM 7-CKA a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent