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Found 4 Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM610463'
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM610463(BDBM610464 | BDBM610465 | N-(4-(2-Methylmorpholino...)
Affinity DataIC50:  0.200nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM610463(BDBM610464 | BDBM610465 | N-(4-(2-Methylmorpholino...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM610463(BDBM610464 | BDBM610465 | N-(4-(2-Methylmorpholino...)
Affinity DataIC50:  0.75nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM610463(BDBM610464 | BDBM610465 | N-(4-(2-Methylmorpholino...)
Affinity DataIC50:  0.800nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB