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Found 3 Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50116222'
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50116222(2-(4-Butyrylamino-phenyl)-8-(2-fluoro-benzyl)-3-{[...)
Affinity DataKi:  7.5nMAssay Description:Ability to inhibit [I125-Tyr5,DLeu6,NMeLeu7,Pro9-NEt]GnRH agonist binding to the cloned human Gonadotropin-releasing hormone receptor was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50116222(2-(4-Butyrylamino-phenyl)-8-(2-fluoro-benzyl)-3-{[...)
Affinity DataKi:  7.5nMAssay Description:Binding affinity at human GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50116222(2-(4-Butyrylamino-phenyl)-8-(2-fluoro-benzyl)-3-{[...)
Affinity DataKi:  7.5nMAssay Description:Binding evaluated in cloned human Gonadotropin-releasing hormone receptor by displacement of [125 I-Tyr, DLeu, NMeLeu, Pro-NEt]GnRH agonistMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed