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Found 2 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-beta' and Ligand = 'BDBM20882'
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM20882(4-[4-(4-benzylpiperazin-1-yl)-1H-pyrazol-3-yl]-6-c...)
Affinity DataIC50:  600nMAssay Description:Binding affinity to Hsp90 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM20882(4-[4-(4-benzylpiperazin-1-yl)-1H-pyrazol-3-yl]-6-c...)
Affinity DataIC50:  600nM EC50:  6.50E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed