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Found 2 Enz. Inhib. hit(s) with Target = 'Hexokinase-4' and Ligand = 'BDBM50447287'
TargetHexokinase-4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50447287(CHEMBL3113999)
Affinity DataIC50:  8.63E+3nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP incubated for 20 mins prior to addition of fluorescein-labeled ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Mus musculus (Mouse))
Amgen

Curated by ChEMBL
LigandPNGBDBM50447287(CHEMBL3113999)
Affinity DataEC50: >1.25E+4nMAssay Description:Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed