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Found 3 Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM186541'
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM186541(US9163021, 209 | US9163021, 222 | US9163021, 224)
Affinity DataIC50:  15.4nMAssay Description:Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat#62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor sou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM186541(US9163021, 209 | US9163021, 222 | US9163021, 224)
Affinity DataIC50:  16.4nMAssay Description:Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat#62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor sou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM186541(US9163021, 209 | US9163021, 222 | US9163021, 224)
Affinity DataIC50:  264nMAssay Description:Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat#62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor sou...More data for this Ligand-Target Pair
In DepthDetails US Patent