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Found 6 Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM50557927'
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50557927(CHEMBL4788009)
Affinity DataKi:  66nMAssay Description:Inhibition of human TRKA at inactive state by kinetic based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50557927(CHEMBL4788009)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of human TRKA at active state by kinetic based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50557927(CHEMBL4788009)
Affinity DataIC50:  39nMAssay Description:Inhibition of human TRKA kinase domain by HTRF KinEASE biochemical assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50557927(CHEMBL4788009)
Affinity DataIC50:  102nMAssay Description:Inhibition of human TRKA at inactive state assessed as inhibition of substrate phosphorylation using fluorescently-labelled peptide as substrate by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50557927(CHEMBL4788009)
Affinity DataIC50:  950nMAssay Description:Inhibition of human TRKA at active state assessed as inhibition of substrate phosphorylation using fluorescently-labelled peptide as substrate by cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50557927(CHEMBL4788009)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human TRKA by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB