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Found 4 Enz. Inhib. hit(s) with Target = 'Histone acetyltransferase p300' and Ligand = 'BDBM188519'
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataIC50:  67nMAssay Description:Inhibition of EP300 bromodomain (unknown origin) incubated for 20 mins by AlphaLISA methodMore data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataIC50:  230nMAssay Description:Inhibition of biotinylated-H4KAc4 binding to human His6-tagged EP300 (A1040 to G1161 residues) expressed in Escherichia coli BL21(DE3) after 2.5 hrs ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataKd:  3.18E+7nMAssay Description:Inhibition of human BRD4 BD1 (67 to 152 residues) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra...More data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataKd:  32nMAssay Description:Binding affinity to human p300 by ITC analysisMore data for this Ligand-Target Pair