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Found 3 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM50398727'
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM50398727(CHEMBL2179247 | US9409858, 1 | US9956192, Compound...)
Affinity DataIC50:  139nMpH: 8.0Assay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM50398727(CHEMBL2179247 | US9409858, 1 | US9956192, Compound...)
Affinity DataIC50:  139nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM50398727(CHEMBL2179247 | US9409858, 1 | US9956192, Compound...)
Affinity DataIC50:  139nMAssay Description:Inhibition of human recombinant HDAC6 expressed in Sf9 cells incubated for 2 hrs using RHKK-Ac fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed