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Found 3 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM163624'
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Florida College of Medicine

LigandPNGBDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
Affinity DataIC50:  720nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Florida College of Medicine

LigandPNGBDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
Affinity DataIC50:  1.31E+4nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Florida College of Medicine

LigandPNGBDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
Affinity DataIC50:  1.31E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent