Found 25 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM19410' 
Affinity DataIC50: >10nMAssay Description:Inhibition of recombinant human HDAC8 using pan-HDAC substrate incubated for 3 hrs by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 181nMAssay Description:Inhibition of Homo sapiens (human) HDAC8More data for this Ligand-Target Pair
Affinity DataIC50: 196nMAssay Description:Inhibition of HDAC8 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of recombinant human HDAC8 using H2N-Arg- His-Lys(Ac)-Lys(Ac)-AMC as substrate incubated for 90 mins and measured after 20 mins by fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of HDAC8 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.88E+3nMAssay Description:Inhibition of human recombinant HDAC8 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
Affinity DataIC50: 9.88E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorogenic-(RHKKAc) as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.88E+3nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.88E+3nMAssay Description:Inhibition of human HDAC8 using RHKAcKAc as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human full length HDAC8 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of C-terminal His-tagged HDAC8 expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant HDAC8 (unknown origin) incubated for 10 mins using Boc-Lys(acetyl)-AMC fluorogenic substrate by homogeneous fluorescence re...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant HDAC8 (unknown origin) using fluorogenic substrate Boc-Lys (acetyl)-AMC after 20 mins by homogeneous fluorescence release a...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.5Assay Description:Biochemical assays of HDAC activity were carried out by Nanosyn in a reaction volume of 10 ul in 384-well microplates. A standard enzymatic reaction ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) using FAM-RHKK(Ac)-NH2/FAM-RHKK(trifluoroacetyl)-NH2 as substrate preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 cells using Boc-Lys (trifluoroacetyl)-A...More data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of full length C-terminal his-tagged human recombinant HDAC8 (142 to 143 residues) expressed in baculovirus in Sf9 insect cells using Ac-L...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of KDAC8 in human K562 cells using [3H]acetylated histone as substrate incubated for 10 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
Affinity DataIC50: 4.49E+4nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
Affinity DataIC50: 6.34E+4nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
Affinity DataIC50: 7.65E+4nMAssay Description:Inhibition of human recombinant HDAC8 incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
