Found 19 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM29589' 
Affinity DataKi: 22nMAssay Description:Competitive inhibition of HDAC8 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 105nMAssay Description:Inhibition of human HDAC8More data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of human recombinant HDAC8 using fluorogenic HDAC substrate after 15 mins by fluorimetrc methodMore data for this Ligand-Target Pair
Affinity DataKi: 750nMAssay Description:Inhibition of C-terminal His-fusion tagged/N-terminal Strep-2 tagged recombinant human HDAC8 (1 to 377 residues) expressed in insect cells using Boc-...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC8 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as su...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant HDAC8 using AMC labeled AC-peptide as substrate incubated for 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human His6/GST-tagged HDAC8 expressed in baculovirus infected High5 insect cells using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC a...More data for this Ligand-Target Pair
Affinity DataIC50: 51.9nMAssay Description:The inhibitory activity of panobinostat dissolved in DMSO and that of the HP-β-CD panobinostat adduct (prepared as described in Example 1) were ...More data for this Ligand-Target Pair
Affinity DataIC50: 231nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
Affinity DataIC50: 231nMAssay Description:Inhibition of C-terminal His-tagged full length human recombinant HDAC8 expressed in baculovirus coexpressed in fall armyworm Sf9 cells using carboxy...More data for this Ligand-Target Pair
Affinity DataIC50: 277nMAssay Description:Inhibition of human recombinant HDAC8 using Boc-Lys(triflouroacetyI)-AMC substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 277nMAssay Description:In vitro antagonistic activity against kinin-induced rabbit jugular vein contraction.More data for this Ligand-Target Pair
Affinity DataIC50: 277nMAssay Description:Inhibition of recombinant HDAC8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of his-strep-tagged HDAC8 (unknown origin) expressed in SF9 cells using [3H]acetylated human histone H4 peptide as substrate by scintillat...More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibition of HADC8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of human KDAC8 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
