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Found 2 Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM347015'
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM347015(US10202388, Compound 13 | US10358451, Compound 10)
Affinity DataIC50: <100nMAssay Description:The compounds described in this disclosure were dissolved in 10% DMSO to predefined concentration. All of the reactions were conducted at room temper...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM347015(US10202388, Compound 13 | US10358451, Compound 10)
Affinity DataIC50: <500nMAssay Description:In vitro IDO1 enzymatic activity was determined in a mixture of 50 mM MES buffer at pH 6.5; 200 nM human IDO enzyme, 150 μM L-Tryptophan, 2250 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent