Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Inhibitor of nuclear factor kappa-B kinase subunit beta' and Ligand = 'BDBM50319741'
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319741(2-phenyl-N-(4-(2-(4-sulfamoylphenylamino)pyrimidin...)
Affinity DataIC50:  50nMAssay Description:Inhibition of FLAG-tagged IKKbeta after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319741(2-phenyl-N-(4-(2-(4-sulfamoylphenylamino)pyrimidin...)
Affinity DataIC50:  4.47E+3nMAssay Description:Inhibition of IKKbeta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNFalpha-induced NF-kappaB expressio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed