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Found 2 Enz. Inhib. hit(s) with Target = 'Interleukin-1 beta' and Ligand = 'BDBM398147'
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398147(4-chloro-N-((1-hydroxy-3-methylcyclohexyl)methyl)-...)
Affinity DataIC50:  55nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398147(4-chloro-N-((1-hydroxy-3-methylcyclohexyl)methyl)-...)
Affinity DataIC50:  55nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent