Found 1 Enz. Inhib. hit(s) with Target = 'Isocitrate dehydrogenase [NADP], mitochondrial' and Ligand = 'BDBM279989'
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Homo sapiens (Human))
Agios Pharmaceuticals
Curated by ChEMBL
Agios Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin) transfected using lentiviral expression system in human U87MG cells assessed as reduction in 2-HG co...More data for this Ligand-Target Pair