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Found 2 Enz. Inhib. hit(s) with Target = 'Kallikrein-1' and Ligand = 'BDBM186869'
TargetKallikrein-1(Homo sapiens (Human))
Kalvista Pharmceuticals

US Patent
LigandPNGBDBM186869(US9670157, 35 2,5-Dimethyl-1-(2-p-tolyl-thiazol-4-...)
Affinity DataIC50:  1.00E+4nMAssay Description:KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKallikrein-1(Homo sapiens (Human))
Kalvista Pharmceuticals

US Patent
LigandPNGBDBM186869(US9670157, 35 2,5-Dimethyl-1-(2-p-tolyl-thiazol-4-...)
Affinity DataIC50: >1.00E+4nMAssay Description:KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent