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Found 3 Enz. Inhib. hit(s) with Target = 'LIM domain kinase 1' and Ligand = 'BDBM50072669'
TargetLIM domain kinase 1(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50072669(CHEMBL3410048)
Affinity DataIC50:  53nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Rattus norvegicus)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50072669(CHEMBL3410048)
Affinity DataIC50:  730nMAssay Description:Inhibition of Limk1 in rat A7r5 cells assessed as reduction in cofilin phosphorylation by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50072669(CHEMBL3410048)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of human LIMK1 (321 to 647 residues) expressed in Sf9 cells using dextrin as substrate incubated for 30 mins by micro-scintillation fluid ...More data for this Ligand-Target Pair
In DepthDetails PubMed