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Found 6 Enz. Inhib. hit(s) with Target = 'Lanosterol synthase' and Ligand = 'BDBM50128063'
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128063(Allyl-{6-[3-(4-bromo-phenyl)-benzo[d]isothiazol-6-...)
Affinity DataIC50:  2.88nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128063(Allyl-{6-[3-(4-bromo-phenyl)-benzo[d]isothiazol-6-...)
Affinity DataIC50:  2.90nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128063(Allyl-{6-[3-(4-bromo-phenyl)-benzo[d]isothiazol-6-...)
Affinity DataIC50:  2.90nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128063(Allyl-{6-[3-(4-bromo-phenyl)-benzo[d]isothiazol-6-...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human liver microsome 2,3-OSC after 1 hr by Silica gel plate phosphor imagingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128063(Allyl-{6-[3-(4-bromo-phenyl)-benzo[d]isothiazol-6-...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128063(Allyl-{6-[3-(4-bromo-phenyl)-benzo[d]isothiazol-6-...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed