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Found 4 Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 5D' and Ligand = 'BDBM223320'
TargetLysine-specific demethylase 5D(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM223320(KDOAM-25)
Affinity DataIC50:  27nMAssay Description:Inhibition of KDM5D (unknown origin) in presence of 4 uM 2-OGMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific demethylase 5D(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM223320(KDOAM-25)
Affinity DataIC50:  60nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5D(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM223320(KDOAM-25)
Affinity DataIC50:  69nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5D(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM223320(KDOAM-25)
Affinity DataIC50:  558nMAssay Description:Inhibition of KDM5D (unknown origin) in presence of 300 uM 2-OGMore data for this Ligand-Target Pair
In DepthDetails PubMed