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Found 3 Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM50503514'
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50503514(CHEMBL4522607 | US10626103, Example 55)
Affinity DataIC50:  1nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50503514(CHEMBL4522607 | US10626103, Example 55)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50503514(CHEMBL4522607 | US10626103, Example 55)
Affinity DataEC50:  8nMAssay Description:Inhibition of LSD1 in human THP1 cells assessed as induction of CD11b expression after 4 days by LIVE/DEAD violet staining based FACS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed