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Found 2 Enz. Inhib. hit(s) with Target = 'Lysyl oxidase homolog 2' and Ligand = 'BDBM50232681'
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232681(CHEMBL4099444 | US11358936, Compound 4-11)
Affinity DataIC50:  203nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232681(CHEMBL4099444 | US11358936, Compound 4-11)
Affinity DataIC50: <300nMAssay Description:LOXL2 amine oxidase activity is evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells stably expr...More data for this Ligand-Target Pair
In DepthDetails US Patent