Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'MAP kinase-interacting serine/threonine-protein kinase 2' and Ligand = 'BDBM164243'
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Effector Therapeutics

US Patent
LigandPNGBDBM164243(US9669031, 2 3,3-dimethyl-6-(pyrimidin-4-ylamino)-...)
Affinity DataIC50:  55nMT: 2°CAssay Description:Compounds are screened for Mnk inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Effector Therapeutics

US Patent
LigandPNGBDBM164243(US9669031, 2 3,3-dimethyl-6-(pyrimidin-4-ylamino)-...)
Affinity DataIC50:  57nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Effector Therapeutics

US Patent
LigandPNGBDBM164243(US9669031, 2 3,3-dimethyl-6-(pyrimidin-4-ylamino)-...)
Affinity DataIC50:  57nMAssay Description:Inhibition of full length N-terminal GST-tagged recombinant human MNK2 expressed in baculovirus expression system using Ac-TATKSGSTTKNR-NH2 as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB