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Found 6 Enz. Inhib. hit(s) with Target = 'Macrophage migration inhibitory factor' and Ligand = 'BDBM50240520'
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Ecole Polytechnique FÉDÉRale De Lausanne

LigandPNGBDBM50240520((isothiocyanatomethyl)benzene | BITC, 17 | Benzyls...)
Affinity DataKi:  790nM IC50:  6.50E+3nMpH: 6.5Assay Description:The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Ecole Polytechnique FÉDÉRale De Lausanne

LigandPNGBDBM50240520((isothiocyanatomethyl)benzene | BITC, 17 | Benzyls...)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Ecole Polytechnique FÉDÉRale De Lausanne

LigandPNGBDBM50240520((isothiocyanatomethyl)benzene | BITC, 17 | Benzyls...)
Affinity DataIC50:  530nMAssay Description:Inhibition of human recombinant macrophage migration inhibitory factor tautomerase activity expressed in Escherichia coli DH5alpha using L-dopachrome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Ecole Polytechnique FÉDÉRale De Lausanne

LigandPNGBDBM50240520((isothiocyanatomethyl)benzene | BITC, 17 | Benzyls...)
Affinity DataIC50:  540nMAssay Description:Inhibition of macrophage migration inhibitory factor tautomerase activity in human Jurkat T cells using L-dopachrome methyl ester as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Ecole Polytechnique FÉDÉRale De Lausanne

LigandPNGBDBM50240520((isothiocyanatomethyl)benzene | BITC, 17 | Benzyls...)
Affinity DataIC50:  790nMAssay Description:Inhibition of recombinant human MIF expressed in Escherichia coli BL21(DE3) using L-dopa as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Ecole Polytechnique FÉDÉRale De Lausanne

LigandPNGBDBM50240520((isothiocyanatomethyl)benzene | BITC, 17 | Benzyls...)
Affinity DataKd:  2.90E+3nMAssay Description:Displacement of 4'-(7-Hydroxy-2-oxo-2H-chromen-3-yl)-[1,1'-biphenyl]-4-carboxylic acid from C-terminal His-tagged recombinant human MIF expressed in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed