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Found 6 Enz. Inhib. hit(s) with Target = 'Macrophage migration inhibitory factor' and Ligand = 'BDBM50458539'
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
L2 Diagnostics

Curated by ChEMBL
LigandPNGBDBM50458539(CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...)
Affinity DataIC50:  370nMAssay Description:Inhibition of recombinant biotinylated human MIF tautomerase activity expressed in Escherichia coli BL21 DE3 assessed as reduction in tautomerization...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
L2 Diagnostics

Curated by ChEMBL
LigandPNGBDBM50458539(CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...)
Affinity DataIC50:  400nMAssay Description:Inhibition of recombinant human MIF expressed in Escherichia coli BL21 DE3 binding to recombinant soluble human CD74 receptor ectodomain (73 to 232 r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
L2 Diagnostics

Curated by ChEMBL
LigandPNGBDBM50458539(CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...)
Affinity DataIC50:  810nMAssay Description:Inhibition recombinant human biotin-labeled MIF binding to recombinant human soluble CD47 receptor (73 to 232 residues) preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
L2 Diagnostics

Curated by ChEMBL
LigandPNGBDBM50458539(CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...)
Affinity DataIC50:  810nMAssay Description:Inhibition of recombinant biotinylated human MIF expressed in Escherichia coli BL21 DE3 binding to immobilized soluble human CD74 receptor ectodomain...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
L2 Diagnostics

Curated by ChEMBL
LigandPNGBDBM50458539(CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of MIF-induced IL-8 secretion in human foreskin fibroblasts incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
L2 Diagnostics

Curated by ChEMBL
LigandPNGBDBM50458539(CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...)
Affinity DataKd:  9.04E+3nMAssay Description:Binding affinity to recombinant biotinylated human MIF expressed in Escherichia coli BL21 DE3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed