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Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50078227'
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50078227(1-[2-(2,6-dichloro-phenyl)-7-methyl-5H-thiazolo[3,...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of 1S,3R-ACPD (10 microM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50078227(1-[2-(2,6-dichloro-phenyl)-7-methyl-5H-thiazolo[3,...)
Affinity DataIC50:  3.00E+4nMAssay Description:Antagonist activity at rat mGlu2 expressed in CHO cells assessed as inibition of (1S,3R)-ACPD-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed