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Found 3 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM372982'
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM372982(3-methyl-5-[6-(5- | US10246432, Example 23 | US105...)
Affinity DataKi:  2.14nMAssay Description:After thawing, membrane homogenates were re-suspended in the binding buffer (50 mM HEPES pH 7.5, 150 mM NaCl) to a final assay concentration of 2.5 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM372982(3-methyl-5-[6-(5- | US10246432, Example 23 | US105...)
Affinity DataKi:  2.14nMAssay Description:After thawing, membrane homogenates were re-suspended in the binding buffer (50 mM HEPES pH 7.5, 150 mM NaCl) to a final assay concentration of 2.5 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM372982(3-methyl-5-[6-(5- | US10246432, Example 23 | US105...)
Affinity DataKi:  2.14nMAssay Description:Membrane PreparationcDNA encoding the human mGlu5 receptor was transfected into HEK293 cells using the transfection reagent Genejuice (Novagen). Fort...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent