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Found 6 Enz. Inhib. hit(s) with Target = 'Mineralocorticoid receptor [729-984]' and Ligand = 'BDBM238163'
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM238163(US10017502, Example 6 | US9394291, 6 | US9394291, ...)
Affinity DataIC50:  13nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM238163(US10017502, Example 6 | US9394291, 6 | US9394291, ...)
Affinity DataIC50:  58nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM238163(US10017502, Example 6 | US9394291, 6 | US9394291, ...)
Affinity DataIC50:  58nMpH: 7.5Assay Description:Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM238163(US10017502, Example 6 | US9394291, 6 | US9394291, ...)
Affinity DataIC50:  82nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM238163(US10017502, Example 6 | US9394291, 6 | US9394291, ...)
Affinity DataIC50:  82nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM238163(US10017502, Example 6 | US9394291, 6 | US9394291, ...)
Affinity DataIC50:  1.90E+3nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent