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Found 4 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50229971'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of ALK5Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of p38-alpha MAPK in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of GST-fused human p38alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of p38alphaChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed