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Found 9 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM325605'
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325605(US9636336, Example 23 | US9636336, Example 86 | US...)
Affinity DataKi:  0.700nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325605(US9636336, Example 23 | US9636336, Example 86 | US...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325605(US9636336, Example 23 | US9636336, Example 86 | US...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325605(US9636336, Example 23 | US9636336, Example 86 | US...)
Affinity DataIC50:  1.30nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325605(US9636336, Example 23 | US9636336, Example 86 | US...)
Affinity DataIC50:  5.5nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325605(US9636336, Example 23 | US9636336, Example 86 | US...)
Affinity DataIC50:  5.5nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325605(US9636336, Example 23 | US9636336, Example 86 | US...)
Affinity DataIC50:  55nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(RAT)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM325605(US9636336, Example 23 | US9636336, Example 86 | US...)
Affinity DataIC50:  63nMAssay Description:Antagonist activity at muscarinic M3 receptor in rat trachea assessed as inhibition of carbachol-induced contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM325605(US9636336, Example 23 | US9636336, Example 86 | US...)
Affinity DataIC50:  63.1nMAssay Description:Antagonist activity at muscarinic M3 receptor in rat trachea assessed as inhibition of carbachol-induced contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed