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Found 4 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M4' and Ligand = 'BDBM50071171'
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50071171(9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataKi:  7.10nMAssay Description:Inhibition of [3H]NMS binding to human muscarinic acetylcholine receptor M4 in transfected CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50071171(9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataIC50:  91nMAssay Description:Evaluated for its binding affinity at human muscarinic receptor m4 by the displacement of [3H]NMS binding using membranes from transfected chinese ha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50071171(9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human muscarinic M4 receptor expressed in CHO cells assessed as blockade of carbachol-induced inhibition of forskolin-stimulat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50071171(9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataEC50:  54nMAssay Description:Antagonist activity at human muscarinic M4 receptor expressed in CHO cells assessed as blockade of carbachol-induced inhibition of forskolin-stimulat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed