Found 7 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M5' and Ligand = 'BDBM10759' TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataKi: 9.77E+3nMAssay Description:Displacement of [3H]NMS from human cloned muscarinic M5 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataEC50: 790nMAssay Description:Activation of M5-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signalMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataEC50: 1.20nMAssay Description:Agonist activity at human muscarinic M5 receptor expressed in BHK-21 cells assessed as calcium mobilization for 6 mins by Calcium4-based stainingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataEC50: 1.20nMAssay Description:Agonist activity at human muscarinic M5 receptor expressed in BHK-21 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataEC50: 630nMAssay Description:Agonistic activity against muscarinic acetylcholine receptor M5 expressed in NIH 3T3 cells.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataEC50: 19nMAssay Description:Agonist activity at human muscarinic M5 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assayMore data for this Ligand-Target Pair
