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Found 2 Enz. Inhib. hit(s) with Target = 'NAD(+) hydrolase SARM1' and Ligand = 'BDBM651963'
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Washington University

US Patent
LigandPNGBDBM651963(US11903935, Compound IA-6)
Affinity DataIC50:  3.20E+3nMAssay Description:This assay is an adaptation of the NAD+/NADH Glo assay (Promega G9071). In this assay, NAD+ cycling enzymes convert NAD+ into NADH. In the presence o...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Washington University

US Patent
LigandPNGBDBM651963(US11903935, Compound IA-6)
Affinity DataIC50:  3.30E+3nMAssay Description:Reaction mixtures were prepared on ice by mixing 10 ul of SARM1 SAM-TIR cell lysate (320 fold dilution of lysate 11-3-2016, or 80 fold lysate dilutio...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent