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Found 2 Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase sirtuin-1' and Ligand = 'BDBM50363784'
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50363784(CHEMBL1945266 | US9365508, 311d (3,4-Cl2))
Affinity DataIC50:  7.09E+4nMAssay Description:Inhibition of recombinant human SitT1 by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50363784(CHEMBL1945266 | US9365508, 311d (3,4-Cl2))
Affinity DataIC50:  7.09E+4nMAssay Description:All compounds were tested for inhibition of SIRT1 and SIRT2 using human recombinant enzymes available in the Fluor de Lys fluorescence-based assay ki...More data for this Ligand-Target Pair
In DepthDetails US Patent