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Found 3 Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase sirtuin-2' and Ligand = 'BDBM333453'
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM333453(US9737525, Compound MIND4)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Phosphodiesterase 2 from pig coronary arteryMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM333453(US9737525, Compound MIND4)
Affinity DataIC50:  1.70E+3nMAssay Description:Modulation of sirtuin activity by compounds was assessed using the Flour de Lys fluorescent biochemical assay in a 96-well format as described (Outei...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM333453(US9737525, Compound MIND4)
Affinity DataIC50:  3.50E+3nMAssay Description:Modulation of sirtuin activity by compounds was assessed using the Flour de Lys fluorescent biochemical assay in a 96-well format as described (Outei...More data for this Ligand-Target Pair
In DepthDetails US Patent