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Found 4 Enz. Inhib. hit(s) with Target = 'Neutrophil elastase' and Ligand = 'BDBM50063719'
TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50063719(2-Isopropylamino-5-methyl-benzo[d][1,3]oxazin-4-on...)
Affinity DataKi:  1.5nMAssay Description:Rate of deacylation by human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50063719(2-Isopropylamino-5-methyl-benzo[d][1,3]oxazin-4-on...)
Affinity DataKi:  1.58nM Kon:  0.0000178M-1s-1 Koff:  1.18E+4s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50063719(2-Isopropylamino-5-methyl-benzo[d][1,3]oxazin-4-on...)
Affinity DataIC50:  33nMAssay Description:Inhibitory concentration against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50063719(2-Isopropylamino-5-methyl-benzo[d][1,3]oxazin-4-on...)
Affinity DataKon:  0.0000180M-1s-1Assay Description:Rate of deacylation by human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed