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Found 2 Enz. Inhib. hit(s) with Target = 'Nicotinamide phosphoribosyltransferase' and Ligand = 'BDBM50435361'
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50435361(CHEMBL2391581 | US11279687, Compound 93)
Affinity DataIC50:  16nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50435361(CHEMBL2391581 | US11279687, Compound 93)
Affinity DataIC50:  26nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed