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Found 3 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma [258-518,Y502F]' and Ligand = 'BDBM231233'
TargetNuclear receptor ROR-gamma [258-518,Y502F](Artificial Sequence)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM231233(US9346782, 13a | US9346782, 13b | US9346782, 13c)
Affinity DataIC50:  46nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [258-518,Y502F](Artificial Sequence)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM231233(US9346782, 13a | US9346782, 13b | US9346782, 13c)
Affinity DataIC50:  52nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [258-518,Y502F](Artificial Sequence)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM231233(US9346782, 13a | US9346782, 13b | US9346782, 13c)
Affinity DataIC50:  200nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent