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Found 4 Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-alpha' and Ligand = 'BDBM23840'
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
University of Tokyo

LigandPNGBDBM23840(2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindo...)
Affinity DataIC50:  9.80E+3nMT: 2°CAssay Description:Human embryonic kidney (HEK) 293 cells were cultured in D-MEM medium. Transfections were performed by the calcium phosphate coprecipitation method. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
University of Tokyo

LigandPNGBDBM23840(2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindo...)
Affinity DataIC50:  9.80E+3nMAssay Description:Antagonist activity at human LXRalpha expressed in HEK293 cells assessed as inhibition of beta-galactosidase activity by luciferase reporter gene ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
University of Tokyo

LigandPNGBDBM23840(2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindo...)
Affinity DataIC50:  9.80E+3nMAssay Description:Antagonist activity at human recombinant LXRalpha expressed in HEK293 cells assessed as inhibition of T0901317-induced transcriptional activation by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
University of Tokyo

LigandPNGBDBM23840(2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindo...)
Affinity DataIC50:  1.30E+4nMAssay Description:Antagonist activity at human LXR-alpha transfected in HEK293 cells after 16 hrs by luciferase reporter gene assay in presence of 0.3 uM N-(4-(1,1,1,3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed