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Found 3 Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-alpha' and Ligand = 'BDBM50179869'
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50179869(CHEMBL203682 | N-methyl-N-[4-(2,2,2-trifluoro-1-hy...)
Affinity DataIC50:  40nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRalpa by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50179869(CHEMBL203682 | N-methyl-N-[4-(2,2,2-trifluoro-1-hy...)
Affinity DataEC50:  3.76E+3nMAssay Description:Agonist activity against human LXRalpha expressed in human HEK293T cells co-expressing CMX-GAL4N-hLXRalpha incubated for 24 hrs by reporter gene assa...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50179869(CHEMBL203682 | N-methyl-N-[4-(2,2,2-trifluoro-1-hy...)
Affinity DataEC50:  200nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed