Found 3 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM50585247' TargetP2X purinoceptor 7(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human P2X7R expressed in HEK293 cells assessed as inhibition of ATP-induced inward current at -60 mV preincubated for 30 mins ...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human P2X7R expressed in HEK293 cells assessed as inhibition of ATP-induced inward current at -60 mV preincubated for 30 mins ...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human P2X7R expressed in HEK293 cells assessed as reduction in YO-PRO-1 iodide dye uptake preincubated for 30 mins followed by...More data for this Ligand-Target Pair
