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Found 3 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase regulatory subunit beta' and Ligand = 'BDBM368718'
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM368718(US10227350, Compound 133 | US10227350, Compound 13...)
Affinity DataIC50:  2nMAssay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM368718(US10227350, Compound 133 | US10227350, Compound 13...)
Affinity DataIC50:  5nMAssay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM368718(US10227350, Compound 133 | US10227350, Compound 13...)
Affinity DataIC50:  400nMAssay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent