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Found 2 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50427488'
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Signal Rx Pharmaceuticals

US Patent
LigandPNGBDBM50427488(CHEMBL2326956 | US10308662, Compound 100 | US95057...)
Affinity DataIC50:  55.2nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Signal Rx Pharmaceuticals

US Patent
LigandPNGBDBM50427488(CHEMBL2326956 | US10308662, Compound 100 | US95057...)
Affinity DataIC50:  80nMAssay Description:Inhibition of PI3K p110alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed