Found 4 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta' and Ligand = 'BDBM25045'
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Astellas Pharma
Astellas Pharma
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Astellas Pharma
Astellas Pharma
Affinity DataIC50: 10nMAssay Description:Inhibition of PI3Kc2betaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Astellas Pharma
Astellas Pharma
Affinity DataIC50: 26nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Astellas Pharma
Astellas Pharma
Affinity DataKd: 10nMAssay Description:Binding constant for PIK3C2B kinase domainMore data for this Ligand-Target Pair