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Found 4 Enz. Inhib. hit(s) with Target = 'Phosphodiesterase' and Ligand = 'BDBM320706'
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM320706((R)- or (S)-1-(1-(4-(1,1- Difluoroethyl)-3- fluoro...)
Affinity DataKi:  0.0550nMAssay Description:Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM320706((R)- or (S)-1-(1-(4-(1,1- Difluoroethyl)-3- fluoro...)
Affinity DataKi:  0.130nMAssay Description:Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM320706((R)- or (S)-1-(1-(4-(1,1- Difluoroethyl)-3- fluoro...)
Affinity DataKi:  1.10nMAssay Description:Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM320706((R)- or (S)-1-(1-(4-(1,1- Difluoroethyl)-3- fluoro...)
Affinity DataKi:  3.10nMAssay Description:Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent