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Found 9 Enz. Inhib. hit(s) with Target = 'Phospholipase D1' and Ligand = 'BDBM50206160'
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206160(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Affinity DataIC50:  8nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206160(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Affinity DataIC50:  11nMT: 2°CAssay Description:Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206160(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Affinity DataIC50:  21nMAssay Description:Inhibition of PLD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206160(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206160(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Affinity DataIC50:  220nMAssay Description:Inhibition of PLD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206160(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Affinity DataIC50:  220nMT: 2°CAssay Description:PLD in vitro enzymatic assay using phospholipase D1(PLD1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206160(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Affinity DataIC50:  310nMT: 2°CAssay Description:PLD in vitro enzymatic assay using phospholipase D2(PLD2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206160(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Affinity DataEC50:  21nMT: 2°CAssay Description:cell-based assay using human non-small-cell lung cancer cell line, Calu-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206160(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Affinity DataEC50:  300nMT: 2°CAssay Description:cell-based assay using HEK293-gfpPLD2 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed