Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Plasma kallikrein' and Ligand = 'BDBM283374'
TargetPlasma kallikrein(Homo sapiens (Human))
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM283374(N-((6-amino-5-cyano-2-methylpyridin-3- yl)methyl)-...)
Affinity DataIC50:  26nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM283374(N-((6-amino-5-cyano-2-methylpyridin-3- yl)methyl)-...)
Affinity DataIC50:  5.50E+3nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM283374(N-((6-amino-5-cyano-2-methylpyridin-3- yl)methyl)-...)
Affinity DataIC50:  5.50E+3nMpH: 7.5Assay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM283374(N-((6-amino-5-cyano-2-methylpyridin-3- yl)methyl)-...)
Affinity DataIC50:  5.50E+3nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent