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Found 12 Enz. Inhib. hit(s) with Target = 'Plasminogen activator inhibitor 1' and Ligand = 'BDBM50149275'
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50149275(2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50149275(2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibitory concentration against Plasminogen activator inhibitor-1 by antibody assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50149275(2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of human glycosylated PAI1 using urokinase type plasminogen activator substrate by direct chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50149275(2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of human non-glycosylated PAI1 using urokinase type plasminogen activator substrate by direct chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50149275(2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50149275(2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of human non-glycosylated PAI1 using tissue type plasminogen activator substrate by direct chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50149275(2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of human glycosylated PAI1 using tissue type plasminogen activator substrate by direct chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50149275(2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of vitronectin binding to human PAI1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50149275(2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...)
Affinity DataIC50:  1.48E+4nMAssay Description:Inhibition of human Plasminogen activator inhibitor 1 using HRP substrate after 30 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50149275(2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...)
Affinity DataKd:  480nMAssay Description:Binding affinity of the compound to towards NBD-labeled S119C Plasminogen activator inhibitor-1 mutant in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50149275(2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity to human immobilized PAI1 by surface plasmon resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50149275(2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...)
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity of compound towards latent Plasminogen activator inhibitor-1 expressed as apparent KdMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed